![]() ![]() If we look at the list of adverse effects associated with this drug (as provided by Wikipedia – Topamax), it is clear that Topamax is not very safe. The reasons for such a turn of events is unclear how can a drug that fails approval for a diet pill suddenly be a perfect match for seizures and migraines? Don’t we all wish for sugar pill to be a pain killer? Unfortunately, sugar or sugar substitutes do not have such serious adverse effects as Topamax (they happen to have different ones). It also received approval for use against migraines. Topamax is a sugar substitute that failed as a diet pill but is somehow permitted by the FDA to be used for epileptic seizures. Personally, I have heard of many cases where it in fact has done just that. However, since the voltage dependent calcium channel is a high voltage channel, for some people the discontinuation may end in seizures.Įvidence is also accumulating that Topamax can cause brain damage 4. The most difficult problem is that doctors are under the false impression that a drug that blocks the voltage dependent calcium and potassium channels can just be easily stopped by a few days of reduction. Unfortunately, Topamax is difficult to quit. I have yet to find a single person on this drug who is not seriously considering dropping it due to its adverse effects, not to mention that it does not appear to work as a pain killer. Yet over 50% of the new members who join my migraine group arrive with Topamax on their prescription list. ![]() Topamax (an anticonvulsant under additional name Topiramate (generic) and in time release Trokendi XR) is important to discuss because it was initially formulated as a diet pill. Not only is it a diet pill made from sugar derivatives (actually a sugar substitute) but it uses two dangerous methods (blocking both voltage dependent calcium and voltage gated sodium channels at once) to achieve what several classes of drugs normally do separately and thus, with one medicine it affects and potentially damages the two circuits that are critical for brain function. Honestly, off-label prescribing has gone too far! Does Topamax really treat so many disparate conditions that doctors prescribe it for everything, even when it is not FDA approved for these conditions? I must add that Topamax is one of the most dangerous drugs in the prescription market today. I would like to add a 10 th to that: I have broken a nail…can I get Topamax? Illnesses or Conditions for which Topamax is Prescribed What I found is not good. Topamax is prescribed for a broad scope of illnesses for which there is likely little evidence of its efficacy. This led me to do some digging into Topamax. I suspect it cannot and the overreach is driven more by marketing than medicine. I cannot help but wondering, how it is possible that one medication can treat so many disparate illnesses. Each one of them had a different illness and each one of them was prescribed the drug Topamax. ![]() Over the past week alone, I have talked to several people about their doctor visits. ![]()
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